منابع مشابه
Proteolysis: Adaptor, Adaptor, Catch Me a Catch
The ClpXP protease of bacteria can degrade a wide variety of proteins while maintaining remarkable substrate selectivity. New work in Escherichia coli implicates adaptor proteins in enhancing substrate selectivity and regulating the flow of substrates to cellular proteases.
متن کاملCatch bonds
What has been your biggest error? Back at the beginning of this century, I used to say “I am going to spend the rest of my life trapped in a mitochondrion!”. This was because I was convinced that it was never going to be possible to retrieve even partial extinct genomes. Now, there are genomic sequences for many ancient humans and animals. This goes back to the famous Arthur C. Clarke quote: “W...
متن کاملLeukocyte Adhesion: What's the Catch?
A recent study shows that the leukocyte adhesion molecules known as selectins form 'catch' bonds, the dissociation rate of which decreases with increasing applied force. The ability of selectins to switch between catch and slip bonds, where dissociation increases with force, can explain the shear threshold effect, in which leukocyte adhesion goes through a maximum with increasing shear rate.
متن کاملOn Second Atom-Bond Connectivity Index
The atom-bond connectivity index of graph is a topological index proposed by Estrada et al. as ABC (G) uvE (G ) (du dv 2) / dudv , where the summation goes over all edges of G, du and dv are the degrees of the terminal vertices u and v of edge uv. In the present paper, some upper bounds for the second type of atom-bond connectivity index are computed.
متن کاملCatch estimation in the presence of declining catch rate due to gear saturation.
One strategy for estimating total catch is to employ two separate surveys that independently estimate total fishing effort and catch rate with the estimator for total catch formed by their product. Survey designs for estimating catch rate often involve interviewing the fishermen during their fishing episodes. Such roving designs result in incomplete episode data and characteristically have empl...
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ژورنال
عنوان ژورنال: Nature
سال: 2001
ISSN: 0028-0836,1476-4687
DOI: 10.1038/35082679